NTVH - 2017, nummer 5, july 2017
dr. D.M. Heijink , dr. M.D. Hazenberg
‘Checkpoint’-remmers vormen een nieuwe, veelbelovende strategie voor de behandeling van lymfomen. Lymfoomcellen worden zonder interventie vaak niet geëradiceerd door het immuunsysteem vanwege de activatie van zogenoemde ‘immune checkpoints’. De werking van deze ‘checkpoints’, hun farmacotherapeutische remmers en het effect van remming van deze eiwitten in de klinische setting wordt besproken voor patiënten met hodgkin- en non-hodgkinlymfoom.
(NED TIJDSCHR HEMATOL 2017;14:226–32)
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